US Highway 281 in Kansas

Communities

Driving along Highway 281 is one of the best ways to experience North Central and South Central Kansas. Forget bumper-to-bumper traffic. The small-town vibes felt along this highway are perfect for those who enjoy a quiet and relaxing getaway. Explore communities where famous Kansas have lived, such as Russell, the hometown of former Senator and Presidential Candidate: Bob Dole. Also, don't forget to visit Medicine Lodge, which gives you access to the scenic detour towards the Gypsum Hills Scenic Byway and the Carrie Nation Stockade Museum

North Central

Lebanon

Lebanon is located on Hwy 281 north of Hwy 36 about a mile. Here you might want to stop by Ladow’s Market for a treat. 

Smith Center

Smith Center, county seat of Smith County has many attractions. Wagner park and the Old Dutch Mill, The Smith Co. Courthouse, In front of…

Osborne

Osborne is a city in the Northcentral hills of Kansas. Find restaurants, motels, B&Bs, and hunting lodges. The city is an ideal place…

Luray

Find nearby attractions and things to do in Luray. The city is 17 miles from Lucas Park Recreation Area, Wilson State Park, and Minooka Park…

Russell

Explore the hometown of former U.S. Senator and 1996 presidential candidate, Bob Dole (1923 - 2021)

South Central

Hoisington

Welcome to Hoisington, where unforgettable outdoor experiences are all around.

Great Bend

Shop, Stay, Play, Grow and EXPLORE Great Bend! Located in the very center of our beautiful state, Great Bend has something for everyone…

St. John

Explore St. John's famous downtown city square and small town charm.

Pratt

Welcome to Pratt, the "Gateway to the High Plains." Find things to do including restaurants, museums, hotels, and trails!

Medicine Lodge

Known as the “Gateway to the Gyp Hills,” Medicine Lodge is a unique and historic community established in 1873.

Plan Your Road Trip

Food & Drink

Find amazing food and beverages while on Highway 281 in Kansas!

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